July 14, 2008

Eric R. Goedken, Andrew I. Gagnon, Gary T. Overmeyer, Junjian Liu, Richard A. Petrillo, Andrew F. Burchat, and Medha J. Tomlinson

HTRF-Based Assay for Microsomal Prostaglandin E₂ Synthase-1 Activity
J Biomol Screen first published on July 14, 2008 as doi:10.1177/1087057108321145
[Abstract] [OnlineFirst[PDF]]  

Kenneth W. Yip, Paulo H. C. Godoi, Dayong Zhai, Xochella Garcia, Jason F. Cellitti, Michael Cuddy, Motti Gerlic, Ya Chen, Arnold Satterthwait, Stefan Vasile, Eduard Sergienko, and John C. Reed

A TR3/Nur77 Peptide-Based High-Throughput Fluorescence Polarization Screen for Small Molecule Bcl-B Inhibitors
J Biomol Screen first published on July 14, 2008 as doi:10.1177/1087057108320918
[Abstract] [OnlineFirst[PDF]]  

Jeong-Joong Yoon, Dhruv Chawla, Tanja Paal, Maina Ndungu, Yuhong Du, Serdar Kurtkaya, Aiming Sun, James P. Snyder, and Richard K. Plemper

High-Throughput Screening-Based Identification of Paramyxovirus Inhibitors
J Biomol Screen first published on July 14, 2008 as doi:10.1177/1087057108321089
[Abstract] [OnlineFirst[PDF]]  

Philip Newton, Paula Harrison, and Stephen Clulow

A Novel Method for Determination of the Affinity of Protein: Protein Interactions in Homogeneous Assays
J Biomol Screen first published on July 14, 2008 as doi:10.1177/1087057108321086
[Abstract] [OnlineFirst[PDF]]  

Damian J. Krysan and Louis Didone

A High-Throughput Screening Assay for Small Molecules That Disrupt Yeast Cell Integrity
J Biomol Screen first published on July 14, 2008 as doi:10.1177/1087057108320713
[Abstract] [OnlineFirst[PDF]]  

Timothy K. Nadler, Christine Rauh-Adelmann, Cheryl Murphy, Amy B. Hall, James R. Graham, Lucy Yen, Neal F. Gordon, and Jeffrey A. Radding

Profiling Protein Tyrosine Phosphorylation : A Quantitative 45-Plex Peptide-Based Immunoassay
J Biomol Screen first published on July 14, 2008 as doi:10.1177/1087057108319978
[Abstract] [OnlineFirst[PDF]]  

July 3, 2008

Rikke L. Schrøder, Søren Friis, Morten Sunesen, Chris Mathes, and Niels J. Willumsen

Automated Patch-Clamp Technique: Increased Throughput in Functional Characterization and in Pharmacological Screening of Small-Conductance Ca²⁺ Release-Activated Ca²⁺ Channels
J Biomol Screen first published on July 3, 2008 as doi:10.1177/1087057108320274
[Abstract] [OnlineFirst[PDF]]  

Holger Erfle, Rainer Pepperkok, Jan Ellenberg, Jutta Bulkescher, Beate Neumann, and Phill Rogers

Work Flow for Multiplexing siRNA Assays by Solid-Phase Reverse Transfection in Multiwell Plates
J Biomol Screen first published on July 3, 2008 as doi:10.1177/1087057108320133
[Abstract] [OnlineFirst[PDF]]  

July 1, 2008

Jie Gao, Yanni Xu, Yuan Yang, Yi Yang, Zhihui Zheng, Wei Jiang, Bin Hong, Xuguang Yan, and Shuyi Si

Identification of Upregulators of Human ATP-Binding Cassette Transporter A1 via High-Throughput Screening of a Synthetic and Natural Compound Library
J Biomol Screen first published on July 1, 2008 as doi:10.1177/1087057108320545
[Abstract] [OnlineFirst[PDF]]  

Marta Maroto, Yolanda Fernandez, Juan Ortin, Fernando Pelaez, and M. Angeles Cabello

Development of an HTS Assay for the Search of Anti-influenza Agents Targeting the Interaction of Viral RNA with the NS1 Protein
J Biomol Screen first published on July 1, 2008 as doi:10.1177/1087057108318754
[Abstract] [OnlineFirst[PDF]]  

June 30, 2008

Steven A. Titus, Li Xiao, Noel Southall, Jianming Lu, James Inglese, Michael Brasch, Christopher P. Austin, and Wei Zheng

A Cell-Based PDE4 Assay in 1536-Well Plate Format for High-Throughput Screening
J Biomol Screen first published on June 30, 2008 as doi:10.1177/1087057108319977
[Abstract] [OnlineFirst[PDF]]  

June 19, 2008

Tony A. Klink, Karen M. Kleman-Leyer, Andrew Kopp, Thane A. Westermeyer, and Robert G. Lowery

Evaluating PI3 Kinase Isoforms Using Transcreener^TM ADP Assays
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108319864
[Abstract] [OnlineFirst[PDF]]  

Paul M. Keller, Timothy Rust, Dennis J. Murphy, Rosalie Matico, John J. Trill, John A. Krawiec, Anthony Jurewicz, Michael Jaye, Mark Harpel, Sara Thrall, and Benjamin Schwartz

A High-Throughput Screen for Endothelial Lipase Using HDL as Substrate
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108319738
[Abstract] [OnlineFirst[PDF]]  

Weidong Du, Xueling Ma, and E. Marion Schneider

A Direct Immunoassay Assessment of Streptavidin- and N-Hydroxysuccinimide-Modified Biochips in Validation of Serological TNF Responses in Hemophagocytic Lymphohistiocytosis
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108319642
[Abstract] [OnlineFirst[PDF]]  

Mark A. Gilchrist II, Angela Cacace, and David G. Harden

Characterization of the 5-HT_2b Receptor in Evaluation of Aequorin Detection of Calcium Mobilization for Miniaturized GPCR High-Throughput Screening
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108319212
[Abstract] [OnlineFirst[PDF]]  

Sang-Hyeup Lee, Jeong Hee Moon, Eun Ah Cho, Seong-Eon Ryu, and Myung Kyu Lee

Monoclonal Antibody-Based Screening Assay for Factor-Inhibiting Hypoxia-Inducible Factor Inhibitors
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108318800
[Abstract] [OnlineFirst[PDF]]  

Elena Fossati, Jordan P. Volpato, Lucie Poulin, Vanessa Guerrero, David-Antoine Dugas, and Joelle N. Pelletier

2-Tier Bacterial and In Vitro Selection of Active and Methotrexate-Resistant Variants of Human Dihydrofolate Reductase
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108318783
[Abstract] [OnlineFirst[PDF]]  

Bin Zhang, Xiubin Gu, Uma Uppalapati, Mark A. Ashwell, David S. Leggett, and Chang J. Li

High-Content Fluorescent-Based Assay for Screening Activators of DNA Damage Checkpoint Pathways
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108318509
[Abstract] [OnlineFirst[PDF]]  

Vivek C. Abraham, Danli L. Towne, Jeffrey F. Waring, Usha Warrior, and David J. Burns

Application of a High-Content Multiparameter Cytotoxicity Assay to Prioritize Compounds Based on Toxicity Potential in Humans
J Biomol Screen first published on June 19, 2008 as doi:10.1177/1087057108318428
[Abstract] [OnlineFirst[PDF]]  

June 2, 2008

D. A. Ross, S. Lee, V. Reiser, J. Xue, K. Alves, S. Vaidya, A. Kreamer, R. Mull, E. Hudak, T. Hare, P. A. Detmers, R. Lingham, M. Ferrer, B. Strulovici, and F. Santini

Multiplexed Assays by High-Content Imaging for Assessment of GPCR Activity
J Biomol Screen first published on June 2, 2008 as doi:10.1177/1087057108317685
[Abstract] [OnlineFirst[PDF]]  

May 28, 2008

Marjo Simonen, Yvonne Ibig-Rehm, Gabriele Hofmann, Johann Zimmermann, Genevieve Albrecht, Maxime Magnier, Valerie Heidinger, and Daniela Gabriel

High-Content Assay to Study Protein Prenylation
J Biomol Screen first published on May 28, 2008 as doi:10.1177/1087057108318757
[Abstract] [OnlineFirst[PDF]]  

May 6, 2008

Paul H. Lee, Steven C. Miller, Carlo van Staden, and Evan F. Cromwell

Development of a Homogeneous High-Throughput Live-Cell G-Protein-Coupled Receptor Binding Assay
J Biomol Screen first published on May 6, 2008 as doi:10.1177/1087057108317835
[Abstract] [OnlineFirst[PDF]]  

February 12, 2008

Christian Parker

Book Review: Antisense Drug Technology, Principles, Strategies and Applications, 2nd Ed
J Biomol Screen first published on February 12, 2008 as doi:10.1177/1087057108314578
[OnlineFirst[PDF]]